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Semiconductor Synthetic Biology Circuits and Communications for Information Storage ( SemiSynBio-III)

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Important Information for Proposers

Any proposal submitted in response to this funding opportunity should be submitted in accordance with the NSF Proposal & Award Policies & Procedures Guide (PAPPG) that is in effect for the relevant due date to which the proposal is being submitted. The NSF PAPPG is regularly revised and it is the responsibility of the proposer to ensure that the proposal meets the requirements specified in this solicitation and the applicable version of the PAPPG. Submitting a proposal prior to a specified deadline does not negate this requirement.

Supports high-risk, high-reward research that addresses scientific and technological challenges associated with the integration of synthetic biology with semiconductor technology.


The National Science Foundation (NSF), through its Divisions of Electrical, Communications and Cyber Systems (ECCS), Computing and Communication Foundations (CCF), Molecular and Cellular Biosciences (MCB), and Materials Research (DMR) announces a solicitation on the Semiconductor Synthetic Biology Circuits and Communications for Information Storage (SemiSynBio-III). Future computing systems with ultra-low energy storage can be built on principles derived from organic systems that are at the intersection of biology, physics, chemistry, materials science, computer science and engineering. Next-generation information storage technologies can be envisioned that are driven by biological principles with use of biomaterials in the fabrication of devices and systems that can store data for more than 100 years with storage capacity 1,000 times more than current storage technologies. Such a research effort can have a significant impact on the future of information storage technologies. This focused solicitation seeks high-risk/high- return interdisciplinary research on novel concepts and enabling technologies that will address the fundamental scientific issues and technological challenges associated with the underpinnings of synthetic biology integrated with semiconductor technology. This research will foster interactions among various disciplines including biology, physics, chemistry, materials science, computer science and engineering that will enable in heretofore-unanticipated breakthroughs.

INFORMATIONAL WEBINAR: The SemiSynBio-III program will host an informational webinar in March 2022 to discuss and answer questions about the solicitation. Details on how to join this webinar will be posted on the program web page.

Updates and announcements

Program contacts

Usha Varshney
uvarshne@nsf.gov (703) 292-5385 ENG/ECCS
Mitra Basu
mbasu@nsf.gov (703) 292-8649 CISE/CCF
Ramon Gonzalez
ramgonza@nsf.gov (703) 292-8046 BIO/MCB
Paul A. Lane
plane@nsf.gov (703) 292-2453 MPS/DMR

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