Molecular Foundations for Biotechnology (MFB)

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Important Information for Proposers

A revised version of the NSF Proposal & Award Policies & Procedures Guide (PAPPG) (NSF 22-1), is effective for proposals submitted, or due, on or after October 4, 2021. Please be advised that, depending on the specified due date, the guidelines contained in NSF 22-1 may apply to proposals submitted in response to this funding opportunity.

Partnerships to Transform Emerging Industries

Supports collaborative high-risk, high-payoff projects that develop new techniques to modify the structure, function and/or fate of biological molecules that have important applications in biotechnology.


This initiative calls for fundamentally new approaches in molecular sciences to drive new directions in biotechnology, a critical and emerging technology of the 21st century. This is the second year of a campaign targeting broad annual themes to be pursued through collaborative high risk/high reward projects.

This year’s solicitation calls for synergistic scientific research collaborations that involve innovative machine learning (ML) methods to foster advances in research on the function of biomolecular systems and have the potential to drive innovation in biotechnology. 

Program contacts

Catalina Achim (703) 292-2048 MPS/CHE
Krastan B. Blagoev (703) 292-4666 MPS/PHY
Zhilan J. Feng (703) 292-7523 MPS/DMS
Wilson A. Francisco (703) 292-7856 BIO/MCB
Tingyu Li (703) 292-4949 MPS/CHE
Marcia E. Newcomer (703) 292-4778
Steven W. Peretti (703) 292-7029 ENG/CBET
Amarda Shehu (703) 292-8191

Awards made through this program

Browse projects funded by this program
Map of recent awards made through this program