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Important Information for Proposers

A revised version of the NSF Proposal & Award Policies & Procedures Guide (PAPPG) (NSF 22-1), is effective for proposals submitted, or due, on or after October 4, 2021. Please be advised that, depending on the specified due date, the guidelines contained in NSF 22-1 may apply to proposals submitted in response to this funding opportunity.


Proposals submitted to this program (including individual and collaborative proposals, GOALIs) must be submitted to the CHE Disciplinary Research Programs solicitation.


  • RUI proposals should be submitted to the RUI Solicitation during the proposal submission window.
  • proposals submitted in response to another solicitation (CAREER)
  • conference proposals (must discuss with a Program Officer before submission)
  • EAGER, RAPID or RAISE proposals (must discuss with a Program Officer before submission)


The Chemical Measurement and Imaging (CMI) Program supports research focusing on chemically-relevant measurement science and chemical imaging, targeting both development of innovative approaches and instruments likely to be of use to the chemistry community and improved understanding of new and existing methods.  Research areas include, but are not limited to, analytical separation science; electroanalytical chemistry; spectrometry (including magnetic resonance and mass spectrometry); and frequency- and time-domain spectroscopy.  Development of new chemical imaging and measurement tools that probe chemical properties and processes is supported.  Innovations enabling the monitoring and imaging of chemical and electronic processes across a wide range of time and length scales are also relevant.  New approaches to data analysis and interpretation (including cheminformatics) are encouraged.  Proposals addressing established techniques must seek improved understanding and/or innovative approaches to substantially broaden applicability.  Sensor-related proposals are expected to address new approaches to chemical sensing, with prospects for broad utility and significant enhancement of current capabilities.

 CMI also accepts proposals that include, but are not limited to, new measurement and imaging approaches that improve on current separation science by requiring less energy or generating less waste, and on harnessing the power of chemical data. 

Submissions that address national needs are encouraged.  These include priority areas associated with sustainability and NSF's Ten Big Ideas. Elements of NSF's Ten Big Ideas particularly relevant to the Division of Chemistry include: Harnessing the Data Revolution, the Quantum Leap, Midscale Instrumentation, Understanding the Rules of Life, and Growing Convergence Research at NSF. Consult NSF Big Ideas solicitations on how these areas match the Division's portfolio. 

Through the Critical Aspects of Sustainability (CAS) program, the Division of Chemistry looks to support basic research aimed at improving the sustainability of resources for future generations while maintaining or improving current products within a global society. 

Proposals addressing development of new instrumentation that enables chemical measurements likely to be of wide interest and utility to the chemistry research community should include the words "Instrument Development:" at the beginning of the title, and include, in the Project Description, consideration of a development timeline, potential utility, and prospects for the extension of the technique to other uses or fields, should it prove viable. 

Industrial partnerships are encouraged through the Grant Opportunities for Academic Liaison with Industry (GOALI) mechanism as means of enhancing use by the greater community, but concepts nearing commercialization are better fits to Small Business Innovation Research (SBIR) or Small Business Technology Transfer (STTR) Programs. 

Proposals integrating innovative computational approaches with CMI-relevant research, such as those enabling efficient and effective data acquisition and analysis, are encouraged and should be submitted to the CMI Program through the Computational and Data Science and Engineering (CDS&E) funding opportunity. 

The CMI Program does not encourage proposals addressing: the development of techniques for topological/morphological imaging; research based on known sensing mechanisms, such as probe synthesis or assembly of array-type devices; or engineering aspects of membrane separations, microfluidics, and/or "lab-on-a-chip" device design, technology, and application.  Proposals on the design and synthesis of novel molecular probes for sensing or contrast agents may be more suitable for the CSDM-B Program.  Proposals for optimizing and/or utilizing established methods for specific applications should be directed to programs focused on the application.  Proposals addressing innovations with anticipated utility primarily in other communities (e.g., biology or materials) are also not encouraged. Proposals with large equipment requests (over $150,000) may be better suited to the Major Research Instrumentation (MRI) Program. 

For recent awards made by the program, search NSF award database with the Program Element Code 6880. 

Program Contacts

Administrative Program Support: Marsha Hawkins, or (703)292-4877

Kelsey D. Cook (703) 292-7490 MPS/CHE
Robin McCarley (703) 292-7514 MPS/CHE
Christopher Elles (703) 292 8840 MPS/CHE

Awards Made Through This Program

Browse projects funded by this program